APPLICATION NOTE: Solvation Studies with Agilitech Single-Use Mixers
Understanding the complexities of solvation and mixing, especially when it comes to solutes like NaCl and NaOH, is crucial for optimizing bioprocesses. While proper mixing might seem straightforward, factors like equipment, method, and solution characteristics play pivotal roles.
Our recent studies have demonstrated that Agilitech’s 10L single-use mixers excel in managing solvation and viscosity challenges across various solutes, including NaCl, NaOH, glucose, HEPES, IgG, and polysorbate 80. These mixers not only ensure macromolecular integrity but also offer reliable temperature control, making them an ideal choice for bioprocess development and manufacturing.
To explore these findings in more depth and see how our 10L SUM can enhance your processes, read the full paper. For collaboration inquiries, reach out to us at info@agilitech.bio.
Application Note Highlights:
Solvation and Mixing Complexity: Modeling solvation free energy and ion/macromolecule behavior in solvents is intricate, with mixing adding further complexities.
Experimental Scope: Conducted experiments on NaCl, NaOH, glucose, HEPES, IgG, and polysorbate 80 to assess solvation and mixing.
Equipment Performance: Agilitech’s 10L single-use mixers effectively handled solvation and viscosity challenges, maintaining macromolecular integrity.
Temperature Control: The 10L stainless steel jacketed mixer demonstrated reliable temperature modulation for solutes.
Application Versatility: Consistent performance across solutes and conditions makes the Agilitech 10L SUM ideal for bioprocess development and manufacturing.
Call for Collaboration: Agilitech invites further collaborations for custom mixing solutions and enhanced process scalability.
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